Dolo 650 side effects: common and serious
Also in: हिन्दी தமிழ் मराठी తెలుగు ಕನ್ನಡ বাংলা ગુજરાતી മലയാളം
Also known as: Dolo, Dolo 650 mg, Dolo 650 tablet, Dolo650
Side effects are uncommon when paracetamol is taken at the right dose. The main danger is liver damage from taking too much.
Dolo 650: Uses, How It Works, Side Effects
- Active ingredient
- Paracetamol 650 mg
- Type of medicine
- Non-opioid analgesics
- Used for
- Fever, Headache, Period pain
- Starts working in
- About 30 to 60 minutes
- Effect lasts
- About 4 to 6 hours
- With or without food
- Either. Food may slow it slightly
- Alcohol
- Avoid heavy or regular drinking
- Pregnancy
- Ask your doctor
- Habit-forming
- No
- Made by
- Micro Labs Ltd
Pharmacist review in progress. This page is based on the sources listed below and is being checked by our registered pharmacist.
Side effects of Dolo 650
Side effects are uncommon when paracetamol is taken at the right dose. The main danger is liver damage from taking too much.
Uncommon or mild
- Feeling sick (nausea)
- A mild skin rash
Rare but serious: get medical help
- Signs of a severe allergic reaction: swelling of the face, lips or throat, difficulty breathing, or a sudden widespread rash
- Red skin with blisters or peeling, which can happen even with first-time use. Stop the medicine and get medical help immediately
- Yellowing of the skin or eyes, dark urine, or pain in the upper right side of the tummy, which can be signs of liver damage
- Unusual bruising, bleeding or frequent infections, which are very rare signs of a blood disorder
Who should be careful
Most people can take paracetamol safely, but some need to check with a doctor first because they are more at risk of liver damage or need a different dose.
- Liver disease, or a history of liver problems
- Drinking alcohol regularly or heavily
- Body weight under 50 kg, malnutrition, or not eating for a long time
- Serious kidney disease
- Pregnancy or breastfeeding: paracetamol is commonly used when needed, but ask your doctor and use the lowest dose for the shortest time
- Past allergic reaction to paracetamol
- Children: use only a children's form at the dose a doctor gives
If someone takes too much
Taking too much paracetamol is a medical emergency, even if the person feels well. Serious liver damage can develop over the next 1 to 3 days with few or no early symptoms. Treatment works best when started within 8 hours, so call 112 or go to the nearest hospital immediately and take the medicine pack with you.
Common questions
Can I drink alcohol while taking Dolo 650?
It is best to avoid alcohol. Regular or heavy drinking makes liver damage from paracetamol more likely. If you drink regularly, ask your doctor what dose is safe for you.
Is Dolo 650 safe during pregnancy?
Paracetamol is commonly used for fever and pain in pregnancy when needed, at the lowest effective dose for the shortest time. Always ask your doctor before taking any medicine while pregnant.
Is Dolo 650 habit-forming?
No. Paracetamol is not addictive and is not a steroid or an opioid.
Sources
- Acetaminophen. StatPearls, National Center for Biotechnology Information (NCBI), US National Library of Medicine
- Paracetamol for adults. NHS (UK)
- Pregnancy, breastfeeding and fertility while taking paracetamol for adults. NHS (UK)
- Acetaminophen Use in Pregnancy and Neurodevelopmental Outcomes (Practice Advisory, Sept 2025). American College of Obstetricians and Gynecologists
- FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen. US Food and Drug Administration (2013)
- Dengue and severe dengue (fact sheet). World Health Organization
- List of drugs prohibited for manufacture and sale through gazette notifications under section 26A of the Drugs & Cosmetics Act 1940. Central Drugs Standard Control Organisation (CDSCO)
- National Formulary of India. Indian Pharmacopoeia Commission
- Pradhan Mantri Bhartiya Janaushadhi Pariyojana. Pharmaceuticals & Medical Devices Bureau of India